MgSO₄ in Eclampsia — Pritchard & Zuspan Regimens for NEET-PG & INICET

This is a high-yield topic in NEET-PG & INICET Obstetrics & Gynecology, contributing 1-2 marks per paper. Master the key concepts below, then practise PYQs on Kinase to lock in your score on exam day.

Quick Answer

MgSO₄ in eclampsia is tested in nearly every NEET-PG & INICET session. Pritchard regimen: 4g IV + 10g IM (5g each buttock) loading, then 5g IM every 4 hours. Zuspan regimen: 4-6g IV bolus, then 1-2g/hour IV infusion. Toxicity = loss of patellar reflex (first sign). Antidote = 10% calcium gluconate IV.

Key Concepts to Lock In

  • 1Pritchard regimen (IV + IM): 4g IV + 10g IM loading, then 5g IM Q4H
  • 2Zuspan regimen (IV only): 4-6g IV bolus, then 1-2g/hr IV infusion
  • 3First sign of toxicity: loss of patellar (knee jerk) reflex
  • 4Therapeutic level: 4-7 mEq/L (4.8-8.4 mg/dL)
  • 5Antidote: 10% Calcium gluconate 1g IV slowly
  • 6Continue MgSO₄ for 24 hours after delivery or last seizure

NEET-PG & INICET Relevance

NEET-PG & INICET SubjectObstetrics & Gynecology
Expected questions1-2 marks per paper
Question typeMostly clinical vignettes; some direct recall
Repeated in last 5 yearsYes — appears in nearly every session

Related High-Yield Topics

Pro tip: reading this page once is not enough. Pair the concepts above with 20-30 NEET-PG & INICET-style PYQs on this topic, then revisit after 7 days. Spaced practice is what locks high-yield topics into long-term recall for exam day.

Frequently Asked Questions

Is MgSO₄ in Eclampsia important for NEET-PG & INICET?
Yes. This topic typically contributes 1-2 marks per paper in the NEET-PG & INICET paper, predominantly in the Obstetrics & Gynecology section. It is among the high-yield topics that consistently appear across recent NEET-PG & INICET sessions.
How should I prepare this topic for NEET-PG & INICET 2026?
Master the key concepts listed on this page, then practise NEET-PG & INICET-style PYQs on this topic. The most efficient approach: 30 minutes of focused reading followed by 20-30 PYQs to lock in retention. Repeat after 7 days for spaced revision.
Where does this topic fit in the NEET-PG & INICET syllabus?
This topic falls under NEET-PG & INICET Obstetrics & Gynecology. Obstetrics & Gynecology carries significant weightage in the NEET-PG & INICET paper. Combine this topic with other high-yield Obstetrics & Gynecology topics for maximum return on study time.
Are PYQs available on this topic in Kinase?
Yes. Kinase has thousands of subject-tagged PYQs including this specific topic. Each question comes with a detailed text explanation covering the concept and why other options are incorrect.
Obstetrics & Gynecology subject
1-2 marks per paper
Updated for NEET-PG & INICET 2026

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