Quick Answer
MgSO₄ in eclampsia is tested in nearly every NEET-PG & INICET session. Pritchard regimen: 4g IV + 10g IM (5g each buttock) loading, then 5g IM every 4 hours. Zuspan regimen: 4-6g IV bolus, then 1-2g/hour IV infusion. Toxicity = loss of patellar reflex (first sign). Antidote = 10% calcium gluconate IV.
Key Concepts to Lock In
- 1Pritchard regimen (IV + IM): 4g IV + 10g IM loading, then 5g IM Q4H
- 2Zuspan regimen (IV only): 4-6g IV bolus, then 1-2g/hr IV infusion
- 3First sign of toxicity: loss of patellar (knee jerk) reflex
- 4Therapeutic level: 4-7 mEq/L (4.8-8.4 mg/dL)
- 5Antidote: 10% Calcium gluconate 1g IV slowly
- 6Continue MgSO₄ for 24 hours after delivery or last seizure
NEET-PG & INICET Relevance
| NEET-PG & INICET Subject | Obstetrics & Gynecology |
| Expected questions | 1-2 marks per paper |
| Question type | Mostly clinical vignettes; some direct recall |
| Repeated in last 5 years | Yes — appears in nearly every session |
Related High-Yield Topics
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