Match each organ with its embryological origin:
Organ:
1. Thyroid
2. Adrenal medulla
3. Kidney
Embryological origin:
a. Ectoderm
b. Intermediate mesoderm
c. Endoderm
d. Neural crest cells
- A.1-a, 2-c, 3-d
- B.1-c, 2-d, 3-b
- C.1-b, 2-c, 3-d
- D.1-c, 2-a, 3-b
Show answer and explanation
Answer: B. 1-c, 2-d, 3-b
The correct answer is 1-c, 2-d, 3-b.
The thyroid arises from endoderm - a median endodermal thickening (thyroid diverticulum) in the floor of the pharynx (1-c). The adrenal medulla develops from neural crest cells (chromaffin cells from adjacent sympathetic ganglia), whereas the adrenal cortex is mesodermal (2-d). The kidney develops from the intermediate mesoderm (pronephros to mesonephros to metanephros) (3-b). Hence 1-c, 2-d, 3-b.
Why the other options are wrong:
- 1-a, 2-c, 3-d: thyroid is endoderm (not ectoderm) and the kidney is intermediate mesoderm (not neural crest).
- 1-b, 2-c, 3-d: thyroid is endoderm (not mesoderm); adrenal medulla is neural crest (not endoderm).
- 1-c, 2-a, 3-b: adrenal medulla is from neural crest, not surface ectoderm - so 2-a is wrong.
High-Yield Facts:
- Thyroid = endoderm (pharyngeal floor diverticulum).
- Adrenal medulla = neural crest; adrenal cortex = mesoderm.
- Kidney and gonads = intermediate mesoderm.
- Neural crest also forms melanocytes, Schwann cells, dorsal root ganglia, and enteric neurons.
Figure: Fates of the germ layers - endoderm (gut/glands), mesoderm (kidney, muscle, circulatory), and ectoderm (skin, nervous system, including neural-crest derivatives).